Essential Biochemistry - Enzymes (Section 1 - No. 39)
In which type of enzyme inhibition does the inhibitor bind to a site distinct from the active site, but changes the shape of the active site?
Competitive inhibition
Non-competitive inhibition
Uncompetitive inhibition
Allosteric regulation
Explication
Non-competitive inhibitors often bind at a site that alters the shape of the active site, thereby reducing enzyme activity.